Yes, you can use NETFILE if you have a balance due.
In TurboTax, follow the prompts on your screen to submit your return through NETFILE. When prompted, select your payment method and file your return. Make sure you pay your balance before the deadline to avoid interest charges.
Note: The CRA’s NETFILE service accepts tax returns for the past four years. You can use TurboTax to NETFILE your returns for tax years 2018 and beyond during the 2021 tax season. Returns for tax years prior to 2018 must be printed and mailed to the CRA.