Thanks for your response. I called CRA and confirmed there were no issues today. I also got the Web Access Code from them. I all the help desk and was given a patch to install - not successful. I was told to print the return - not an option. Then I was asked to install the software on another computer because that seems to solve most problems. The person I talked with was aware of this problem - it is not a problem connecting to CRA - it is a problem with the software not being able to communicate to CRA.
I have turned off Virus software, disabled the firewall, added the software to the firewall, double checked all entries in TuboTax Business, installed the patch - several times. Shut down, restarted...
And now waiting for the updated on the other PC to finish to try to send the file from there.
Not a great day.
