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The Proceeds of Disposition is the selling price of the property and it's usually not the same as the Adjusted Cost Base.
The Adjusted Cost Base is usually the purchase price of the property, plus any expenses incurred to acquire the property and the cost of any additions to it. Examples of expenses would be legal fees, surveyor's fees, and assessment or brokerage fees.
If you've sold your Principal Residence, you'd need to fill out both the PRWS and the T2091 (or Form T1255 for deceased individuals) in TurboTax Desktop. 
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