Yes. Only the sale of a principal residence is
exempt from capital gains/losses.
To do this in TurboTax CD/Download EasyStep mode,
click on Income & Expenses>Investment Profile in the side menu. Check
off “Capital Gains or Losses(shares, properties, etc)” and then click Continue.
To do this in TurboTax CD/Download Forms mode, use
Schedule 3 Part 4 (top of page 2).