If you are employed by a company operating in Canada then TurboTax deluxe would be the best option, if you hope to maximize the amount of deductions. If you have investments, on top of having income, then TurboTax Premier is the best option.
If you would like information on how taxation works for US citizens view the link for full information:
https://turbotax.intuit.ca/tips/the-usa-canada-tax-treaty-explained-14788
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