Do I file two separate returns for my spouse and me now that he is retired, is receiving pension, and is self-employed: a deluxe for me and a self-employed for him?

If you want to use two different version of TurboTax for you and your spouse, then yes, you can prepare your returns separately. 

If you prepare your returns together, you will both be using the same version of TurboTax and both be charged the same price.