Yes, you sure can, as long as your wife is considered disabled, and you have a signed T2201 from your physician.

To claim the Home Accessibility Tax Credit, you will go to your "Deductions" tab - "Payment Profile" and you will see the "Home Accessibility Tax Credit" open it and start from there.

For further information please review the links provided below from TurboTax:

• Home Accessibility Tax Credit (HATC)

• A Guide to the Disability Tax Credit

And from the CRA:

• Home accessibility tax credit (HATC)
• Home accessibility expenses

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