Son has 3885.60 of eligible tuition fees on T2202. His refund is 2195.77. Want to transfer the unused portion on T2202 to wife but have 0$ to transfer. Is this possible?

[TurboTaxKim]

Yes, it is possible if your son needed to use the Tuition and Education Amounts on his own return first. If he needed to use all of the amounts or over $5,000 then he would have Zero to transfer. Any excess would be carried forward on his return.

Without seeing the actual tax return and how much income was made and what type, it's hard to determine from this forum how much of the Tuition is being used. 

Please see this information on transferring and carrying forward tuition: CRA - Transfer or carry forward amount and TurboTax FAQ