You need to report each "sale", so Yes, you will calculate the ACB for each trade. If you buy and sell that particular stock entirely, it's easy to calculate. For example:
It's when you don't completely sell the stock that it get's a little more complicated. CRA requires you to keep a running total of the Adjusted Cost Base (ACB) for tax purposes. When you buy shares, the total ACB is recalculated to be the previous total ACB, plus the total cost of the new shares.
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